Autoimmune & Inflammatory Panel

Antinuclear antibody test — the primary screening tool for autoimmune disease. A positive ANA doesn't diagnose a specific condition, but it signals that your immune system is producing antibodies against your own tissue.

Specific markers for lupus and mixed connective tissue disease. These antibodies target proteins in your cell nuclei and are highly specific for systemic autoimmune conditions.

Double-stranded DNA antibodies are the most specific marker for systemic lupus erythematosus (SLE). Levels often correlate with disease activity and can predict flares.

An antibody found in approximately 80% of rheumatoid arthritis patients. Can be elevated years before joint symptoms appear, enabling early intervention.

Anti-cyclic citrullinated peptide antibody — highly specific for rheumatoid arthritis and often positive before symptoms develop. More specific than rheumatoid factor alone.

Thyroid peroxidase antibodies — the hallmark of Hashimoto's thyroiditis, the most common autoimmune disease in women. Can be elevated for years while TSH remains "normal."

High-sensitivity C-reactive protein measures systemic inflammation. Elevated in active autoimmune disease, infections, and cardiovascular inflammation. Useful for tracking disease activity.

Erythrocyte sedimentation rate — a general inflammation marker that complements hs-CRP. Elevated ESR is common in autoimmune flares, infections, and inflammatory conditions.